Sean Sun

Sean Sun

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Additional Details

Affiliation - John Hopkins University

Title of Talk - Water Dynamics in Cells and Tissues

Abstract

The mammalian cell surface is highly permeable to water. The cell can also actively control the water flux across the cell surface by pumping solutes (mostly ions), and thereby controlling the cell water content and the cell volume. In this talk, we will explore how the cell also uses active water fluxes to move and change cell shape. The same players in the cell volume control system are involved in driving cell movement, especially in high viscosity environments. Mathematical modeling shows that the water-driven cell movement is energetically costly, but is necessary when the hydraulic environment is viscous. Finally, we will discuss how epithelial cell layers such as the kidney tubule pump water and generate mechanical force.

 

Date And Time

Oct 25, 2019 04:00 PM to
Dec 9, 2022 05:00 PM
 

Location

Online Event
 

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