Center Seminars & Workshops
Events
Paul Atzberger
(University of California Santa Barbara)
Surface Fluctuating Hydrodynamics Methods for the Drift-Diffusion Dynamics of Proteins and Microstructures within Curved Lipid Bilayer Membranes
Show/Hide Abstract
We introduce surface fluctuating hydrodynamics approaches for investigating transport and fluid-structure interactions arising in cell mechanics within curved lipid bilayer membranes. We focus particularly on drift-diffusion dynamics of interacting proteins and microstructures. We show how a mesoscale stochastic description of the mechanics can be formulated (SPDEs) accounting for geometric contributions, hydrodynamic coupling, and thermal fluctuations. The underlying stochastic equations (SPDEs) pose practical challenges for use in simulations, including, (i) a need for accurate and stable discretizations of geometric terms and differential operators on curved geometries, (ii) techniques for hydrodynamics handling surface incompressibility constraints, and (iii) stiffness from rapid time-scales introduced by the thermal fluctuations. We show how practical spectral methods and meshfree computational approaches can be developed for simulations over long spatial-temporal scales. We then present results for protein and microstructure interactions within membranes and the roles played by hydrodynamic coupling and geometry. For related simulation software and more information, see http://atzberger.org/
04:00 PM -
Online
Henry Fu
(University of Utah)
04:00 PM -
DRL 4C4
Yuan-Nan Young
(New Jersey Institute of Technology)
04:00 PM -
DRL 4C4
Anna Nelson
(Duke University)
04:00 PM -
DRL 4C4
Tom Powers
(Brown University)
04:00 PM -
DRL 4C4
Laura Schmid
(Korea Advanced Institute of Science and Technology)
-
Online
Fernando Pascoal Dos Santos
(University of Amsterdam)
-
DRL 4C4
Jasmine A. Nirody
(University of Chicago)
04:00 PM -
DRL 4C4
Saverio Spagnolie
(University of Wisconsin, Madison)
04:00 PM -
DRL 4C4
Matt Holzer
(George Mason University.)
04:00 PM -
DRL 4C4
Mary Silber
(University of Chicago)
04:00 PM -
DRL 4C4