Qing Nie

Qing Nie

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Additional Details

Affiliation - University of California, Irvine

Title of Talk - Multiscale inference and modeling of cell fate via single-cell data

Abstract

Cells make fate decisions in response to dynamic environmental and pathological stimuli as well as cell-to-cell communications. Recent technological breakthroughs have enabled to gather data in previously unthinkable quantities at single cell level, starting to suggest that cell fate decision is much more complex, dynamic, and stochastic than previously recognized. Multiscale interactions, sometimes through cell-cell communications, play a critical role in cell decision-making. Dissecting cellular dynamics emerging from molecular and genomic scale in single-cell demands novel computational tools and multiscale models. In this talk, through multiple biological examples we will present our recent effort to use single-cell RNA-seq data and spatial imaging data to uncover new insights in development, regeneration, and cancers. We will also present several new computational tools and mathematical modeling methods that are required to study the complex and dynamic cell fate process through the lens of single cells. Zoom

 

Date And Time

Nov 24, 2020 04:00 PM to
Dec 9, 2022 05:00 PM
 

Location

Online Event
 

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