Alexandria Volkening

Alexandria Volkening

by
16 16 people viewed this event.

Additional Details

Affiliation - Northwestern University

Title of Talk - Modeling and measuring pattern formation in zebuctures

Abstract

Wild-type zebrafish (Danio rerio) are characterized by black and yellow stripes, which form on their body and fins due to the self-organization of thousands of pigment cells. Mutant zebrafish and sibling species in the Danio genus, on the other hand, feature altered, variable patterns, including spots and labyrinth curves. The longterm goal of my work is to better link genotype, cell behavior, and phenotype by helping to identify the specific alterations to cell interactions that lead to these different fish patterns. Using a phenomenological approach, we develop agent-based models to describe the behavior of individual cells and simulate pattern formation on growing domains. In this talk, I will overview our models and highlight how topological techniques can be used to quantitatively compare our simulations with in vivo images. I will also discuss future directions related to taking a more mechanistic approach to modeling cell behavior in zebrafish.

 

Date And Time

Oct 27, 2020 04:00 PM to
Aug 12, 2022 05:00 PM
 

Location

Online Event
 

Event Types

 

Event Category

Share With Friends

0
0
image
https://mathbio.sas.upenn.edu/wp-content/themes/maple/
https://mathbio.sas.upenn.edu/
#084550
style1
paged
Loading posts...
/code/
#
on
none
loading
#
Sort Gallery
on
yes
yes
off
on
off