Welcome to the Codon Volatility Computation Server (v1.0)

This public web server allows users to calculate the volatility and associated volatility
P-values for nucleotide coding sequences. The volatility P-values of genes reflect the
relative selective pressures for or against amino acid changes, as described in the
accompanying paper:

J. B. Plotkin, J. Dushoff, and H. B. Fraser.
Detecting selection using a single genome sequence of M. tuberculosis and P. falciparum.
Nature, 428: 942-945 (2004).

 

 

Enter a name for this analysis (optional):

Please select a genome whose volatility you wish to compute. 

Or upload a file in FASTA format: About Input Files

Specify the transition-transversion bias, kappa:    About Kappa

About Output

More information about the volatility computation can be found  here:
Return to Volatility Home | Plotkin Lab Home
For more information contact Joshua Plotkin at jplotkin@sas.upenn.edu.edu